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Ankylosing Spondylitis
Moderate
Ankylosing spondylitis is a chronic inflammatory condition that mainly affects the spine and the joints connecting the spine and pelvis. It commonly causes lower back or hip pain and stiffness that may worsen after periods of rest and improve with movement. In some people, inflammation can also affect other joints, the eyes, skin, or digestive system.
Body System
Bones & Joints
When to Seek Medical Attention
Ankylosing spondylitis is a chronic inflammatory condition that generally requires ongoing medical care rather than emergency treatment. Seek assessment for persistent inflammatory back pain, stiffness, reduced mobility, or worsening symptoms. Prompt evaluation is appropriate for sudden severe pain, significant neurological symptoms, chest symptoms, or new eye pain and redness.
Symptoms
3
Causes
2
Treatments
5
Diet
3
Overview
Ankylosing spondylitis is a chronic inflammatory condition that mainly affects the spine and the joints connecting the spine and pelvis. It commonly causes lower back or hip pain and stiffness that may worsen after periods of rest and improve with movement. In some people, inflammation can also affect other joints, the eyes, skin, or digestive system.
Symptoms 3
Back Pain
Lower Back Pain
Muscle Weakness
Causes 2
The exact cause of ankylosing spondylitis is unknown. Genetic and environmental factors appear to contribute. The HLA-B27 gene is strongly associated with the condition, although many people who carry this gene never develop ankylosing spondylitis. Other genetic variations and environmental influences may also affect whether the disease develops.
Autoimmune Disorder
Genetics
Risk Factors
Risk factors include a family history of ankylosing spondylitis and genetic susceptibility, particularly the HLA-B27 gene. Symptoms commonly begin before age 45. People with inflammatory bowel diseases such as Crohn disease or ulcerative colitis, or with psoriasis, may also have increased risk of developing ankylosing spondylitis.
Diagnosis
Diagnosis is based on a patient's medical history,
symptoms, physical examination and, when necessary,
laboratory or imaging investigations.
Diagnosis of ankylosing spondylitis is based on symptoms, physical examination, medical history, and imaging. X-rays may show changes in the sacroiliac joints or spine, while MRI can detect inflammation earlier in the disease. Blood tests may include markers such as C-reactive protein and testing for HLA-B27. No single test confirms the condition in every person.
Prevention
Key Prevention Tips
Ankylosing spondylitis cannot currently be prevented because its exact cause is unknown and genetic factors play an important role
People with a strong family history or persistent inflammatory back symptoms should seek medical evaluation
Early diagnosis and appropriate management, including regular physical activity and exercises recommended by healthcare professionals, can help maintain mobility and posture
Prevention Guidance
Ankylosing spondylitis cannot currently be prevented because its exact cause is unknown and genetic factors play an important role. People with a strong family history or persistent inflammatory back symptoms should seek medical evaluation. Early diagnosis and appropriate management, including regular physical activity and exercises recommended by healthcare professionals, can help maintain mobility and posture.
Reminder: Prevention recommendations should be tailored to your personal health status and risk factors.
Treatment & Management 5
Detailed treatment guidance is currently being prepared.
Detailed treatment guidance is currently being prepared.
Detailed treatment guidance is currently being prepared.
Detailed treatment guidance is currently being prepared.
Detailed treatment guidance is currently being prepared.
Medical Note: The treatment information provided is intended for educational purposes only.
Always consult a qualified healthcare professional before starting,
stopping, or changing any treatment.
Diet & Nutrition 3
Recommended Foods
Omega-3 Foods
May reduce inflammation
Fresh Fruits
Rich in antioxidants
Vegetables
Support joint health
Foods to Avoid
Processed Foods
May worsen inflammation
Sugary Foods
Limit intake
Medical Nutrition Note: Diet recommendations are intended for general educational purposes and should be tailored to individual health needs by a qualified healthcare professional.
Frequently Asked Questions 5
A chronic inflammatory disease affecting the spine.
Back pain and stiffness are common.
Yes, exercise improves flexibility and posture.
Immune and genetic factors play a role.
There is no cure but symptoms can be managed.
Helpful Tip: These answers provide general medical information.
Consult your healthcare provider for advice tailored to your condition.