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Endometrial Cancer

Urgent

Endometrial cancer is a cancer that begins in the lining of the uterus, called the endometrium. It is one of the most common cancers of the female reproductive system. Abnormal cells can grow uncontrollably and may invade nearby tissues or spread to other parts of the body. Abnormal vaginal bleeding, particularly bleeding after menopause, is an important symptom that should be evaluated.

Body System
Female Reproductive System
Symptoms
3
Causes
1
Treatments
5
Diet
4

Overview

Endometrial cancer is a cancer that begins in the lining of the uterus, called the endometrium. It is one of the most common cancers of the female reproductive system. Abnormal cells can grow uncontrollably and may invade nearby tissues or spread to other parts of the body. Abnormal vaginal bleeding, particularly bleeding after menopause, is an important symptom that should be evaluated.

Symptoms 3

Itching Persistent Hoarseness Skin Rash

Causes 1

Endometrial cancer develops when cells in the endometrium acquire changes that cause them to grow and divide abnormally. The exact cause is not always known. Hormonal factors, particularly prolonged exposure to estrogen without enough progesterone, can stimulate excessive growth of the uterine lining. Genetic changes and inherited conditions such as Lynch syndrome can also contribute to some cases.
Hormonal Imbalance

Risk Factors

Risk factors include increasing age, obesity, prolonged estrogen exposure, early menstruation, late menopause, never having been pregnant, certain hormone therapies, diabetes, and a family history of endometrial or colorectal cancer. Lynch syndrome and some other inherited genetic conditions can substantially increase risk. Risk varies among individuals and may depend on the combination of hormonal, metabolic, and genetic factors.

Diagnosis

Diagnosis is based on a patient's medical history, symptoms, physical examination and, when necessary, laboratory or imaging investigations.
Diagnosis usually begins with evaluation of abnormal vaginal bleeding or other symptoms and a pelvic examination. Transvaginal ultrasound may be used to assess the thickness and appearance of the endometrium. A definitive diagnosis generally requires sampling the uterine lining, usually with an endometrial biopsy. Hysteroscopy or dilation and curettage may be used when additional tissue evaluation is needed. Imaging can help determine whether cancer has spread.

Prevention

Key Prevention Tips
Endometrial cancer cannot always be prevented, but maintaining a healthy weight, staying physically active, and managing conditions such as diabetes may reduce risk
Hormone therapy should be used according to medical advice, with appropriate consideration of whether estrogen is given with progesterone
People with Lynch syndrome or a strong family history should discuss appropriate risk assessment and screening or preventive options with a healthcare professional
Prevention Guidance
Endometrial cancer cannot always be prevented, but maintaining a healthy weight, staying physically active, and managing conditions such as diabetes may reduce risk. Hormone therapy should be used according to medical advice, with appropriate consideration of whether estrogen is given with progesterone. People with Lynch syndrome or a strong family history should discuss appropriate risk assessment and screening or preventive options with a healthcare professional.
Reminder: Prevention recommendations should be tailored to your personal health status and risk factors.

Treatment & Management 5

Detailed treatment guidance is currently being prepared.

Detailed treatment guidance is currently being prepared.

Detailed treatment guidance is currently being prepared.

Detailed treatment guidance is currently being prepared.

Detailed treatment guidance is currently being prepared.
Medical Note: The treatment information provided is intended for educational purposes only. Always consult a qualified healthcare professional before starting, stopping, or changing any treatment.

Diet & Nutrition 4

Recommended Foods
Fresh Fruits
Provide antioxidants.
Vegetables
Support immune health.
Whole Grains
Support digestive health.
Lean Protein
Supports healing and recovery.
Foods to Avoid
Processed Foods
May worsen metabolic health.
Excess Sugar
May contribute to obesity.
Medical Nutrition Note: Diet recommendations are intended for general educational purposes and should be tailored to individual health needs by a qualified healthcare professional.

Frequently Asked Questions 5

It is cancer that develops in the lining of the uterus.

Abnormal uterine bleeding is a common symptom.

Obesity and hormonal imbalance increase risk.

Biopsy and imaging studies are commonly used.

Early-stage disease is often treatable.
Helpful Tip: These answers provide general medical information. Consult your healthcare provider for advice tailored to your condition.