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Cushing Syndrome
Moderate
Cushing syndrome occurs when the body is exposed to excessive levels of cortisol for a prolonged period. It can result from long-term use of corticosteroid medicines or from conditions that cause the body to produce too much cortisol. Symptoms may include weight gain, changes in skin appearance, muscle weakness, high blood pressure, and changes in blood sugar.
Body System
Neck & Thyroid
When to Seek Medical Attention
Cushing syndrome requires medical assessment because prolonged excess cortisol can affect blood pressure, blood glucose, bones, muscles, and cardiovascular health. Seek prompt evaluation for worsening weakness, uncontrolled blood pressure or diabetes, significant infection, or other progressive symptoms. Emergency assessment is appropriate for severe chest pain, severe shortness of breath, confusion, fainting, or other acute complications.
Symptoms
3
Causes
2
Treatments
5
Diet
3
Overview
Cushing syndrome occurs when the body is exposed to excessive levels of cortisol for a prolonged period. It can result from long-term use of corticosteroid medicines or from conditions that cause the body to produce too much cortisol. Symptoms may include weight gain, changes in skin appearance, muscle weakness, high blood pressure, and changes in blood sugar.
Symptoms 3
Excessive Thirst
Loss Of Speech
Weight Gain
Causes 2
Cushing syndrome can result from taking corticosteroid medicines for a long period or at high doses. It can also occur when the body produces excessive cortisol because of a tumor or other abnormality involving the pituitary gland, adrenal glands, or, less commonly, another part of the body. Pituitary tumors that produce excess ACTH are a common cause of endogenous Cushing syndrome.
Hormonal Imbalance
Stress
Risk Factors
Risk factors depend on the cause. Long-term or high-dose corticosteroid treatment is an important risk factor for medication-related Cushing syndrome. Conditions that cause abnormal ACTH or cortisol production can lead to endogenous disease. A family history of certain endocrine tumors or inherited syndromes may increase the risk of some forms.
Diagnosis
Diagnosis is based on a patient's medical history,
symptoms, physical examination and, when necessary,
laboratory or imaging investigations.
Diagnosis of Cushing syndrome involves determining whether cortisol levels are abnormally high and then identifying the source of excess cortisol. Tests may include measurement of cortisol in urine, saliva, or blood and suppression testing. Once excess cortisol is confirmed, additional blood tests and imaging may be used to determine whether the cause involves the pituitary gland, adrenal glands, or another source.
Prevention
Key Prevention Tips
Cushing syndrome related to corticosteroid medicines may be reduced by using these medicines only as prescribed and at the lowest effective dose for the appropriate duration
Corticosteroids should not be stopped suddenly without medical guidance
People with conditions that can cause excess cortisol should receive appropriate monitoring and treatment to reduce complications
Prevention Guidance
Cushing syndrome related to corticosteroid medicines may be reduced by using these medicines only as prescribed and at the lowest effective dose for the appropriate duration. Corticosteroids should not be stopped suddenly without medical guidance. People with conditions that can cause excess cortisol should receive appropriate monitoring and treatment to reduce complications.
Reminder: Prevention recommendations should be tailored to your personal health status and risk factors.
Treatment & Management 5
Detailed treatment guidance is currently being prepared.
Detailed treatment guidance is currently being prepared.
Detailed treatment guidance is currently being prepared.
Detailed treatment guidance is currently being prepared.
Detailed treatment guidance is currently being prepared.
Medical Note: The treatment information provided is intended for educational purposes only.
Always consult a qualified healthcare professional before starting,
stopping, or changing any treatment.
Diet & Nutrition 3
Recommended Foods
Fresh Vegetables
Support overall health.
Lean Protein
Supports muscle health.
Whole Grains
Provide balanced nutrition.
Foods to Avoid
Excess Salt
May worsen blood pressure.
Sugary Foods
May worsen metabolic problems.
Medical Nutrition Note: Diet recommendations are intended for general educational purposes and should be tailored to individual health needs by a qualified healthcare professional.
Frequently Asked Questions 5
It is a hormonal disorder caused by excessive cortisol levels.
Weight gain, round face and high blood pressure are common.
Excess cortisol production or prolonged steroid use may cause it.
Blood, urine and imaging tests help diagnosis.
Yes, treatment depends on the underlying cause.
Helpful Tip: These answers provide general medical information.
Consult your healthcare provider for advice tailored to your condition.